MLXIP 抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
MLXIP 抗体

MLXIP 抗体

商家询价

产品名称： MLXIP 抗体

英文名称： MLXIP Antibody

产品编号： XY13614-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 MLXIP 抗体

Applications
In-house applications ELISA, WB, IHC, IF, IP     Application not tested? Please see our Guarantee.
Published applications ChIP, IP, WB Publications 3 citations –view here
Species specificity Human,Mouse,Rat; other species not tested.
Published Species Human, mouse
Images
Prev12NextView more validation data
  • 13614-1-AP;K-562 cellK-562 cells were subjected to SDS PAGE followed by western blot with 13614-1-AP(MLXIP antibody) at dilution of 1:500
  • 13614-1-AP;H-skeletal muscleImmunohistochemical of paraffin-embedded human skeletal muscle using 13614-1-AP(MLXIP antibody) at dilution of 1:100 (under 10x lens)
  • 13614-1-AP;H-skeletal muscleImmunohistochemical of paraffin-embedded human skeletal muscle using 13614-1-AP(MLXIP antibody) at dilution of 1:100 (under 40x lens)
  • 13614-1-AP;HepG2 cellsImmunofluorescent analysis of HepG2 cells, using MLXIP antibody 13614-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
  • 13614-1-AP;K-562 cellsIP Result of anti-MLXIP (IP:13614-1-AP, 4ug; Detection:13614-1-AP 1:300) with K-562 cells lysate 3200ug.
Positive WB detected in K-562 cells
Positive IP detected in K-562 cells
Positive IHC detected in Human skeletal muscle tissue
Positive IF detected in HepG2 cells
Recommended dilution WB : 1:500-1:5000
IP : 1:200-1:1000
IHC : 1:20-1:200
IF : 1:10-1:100
 MLXIP 抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen MLXIP fusion protein ag4519 Full name MLX interacting protein
Calculated molecular
weight		 919aa,100 kDa Observed molecular 
weight		 130 kDa
GenBank accession 
number		 BC039704 Gene ID (NCBI) 22877
Gene symbol MLXIP Synonyms BHLHe36, KIAA0867, MIR, MLX interacting protein, MLXIP, MONDOA
Background MLXIP 抗体

Mlx-interacting protein(MLXIP), after forming heterodimers with MLX, can bind to and then activate transcription from CACGTG E boxes. The N terminus of MLXIP acts as a CRM1-dependent nuclear export signal and contribute to the cytoplasmic localization of the complex, and as a binding site for 13 protein. the C terminus contains a cytoplasmic localization signal and mediates protein-protein interaction of MONDOA and MLX. The complex play a role in transcriptional activation of glycolytic target genes and glucose-responsive gene regulation. This antibody could recognize isoform1(~110kd) and isoform3(~69kd) of MLXIP. MLXIP 抗体

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