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上海信裕生物科技有限公司
MICAL2抗体

MICAL2抗体

商家询价

产品名称： MICAL2抗体

英文名称： MICAL2Antibody

产品编号： XY 13965-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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  • 邮编 : 200612
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 MICAL2抗体

Applications
In-house applications ELISA, IHC, IF, WB, IP     Application not tested? Please see our Guarantee.
Species specificity Human,Mouse,Rat; other species not tested.
Images
Prev12NextView more validation data
  • 13965-1-AP;H-brainImmunohistochemical of paraffin-embedded human brain using 13965-1-AP(MICAL2 antibody) at dilution of 1:100 (under 10x lens)
  • 13965-1-AP;H-brainImmunohistochemical of paraffin-embedded human brain using 13965-1-AP(MICAL2 antibody) at dilution of 1:100 (under 40x lens)
  • 13965-1-AP;HepG2Immunofluorescent analysis of HepG2 cells, using MICAL2 antibody 13965-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
  • 13965-1-AP;PC-3 cellsPC-3 cells were subjected to SDS PAGE followed by western blot with 13965-1-AP( MICAL2 Antibody) at dilution of 1:300
  • 13965-1-AP;PC-3 cellsIP Result of anti-MICAL2 (IP:13965-1-AP, 5ug; Detection:13965-1-AP 1:300) with PC-3 cells lysate 5000ug.
Positive WB detected in PC-3 cells
Positive IP detected in PC-3 cells
Positive IHC detected in Human brain tissue
Positive IF detected in HepG2 cells
Recommended dilution WB : 1:200-1:1000
IP : 1:200-1:1000
IHC : 1:20-1:200
IF : 1:10-1:100
 MICAL2抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen MICAL2 fusion protein ag4950 Full name Microtubule associated monoxygenase, calponin and LIM domain containing 2
Calculated molecular
weight		 127 kDa Observed molecular 
weight		 95, 112 kDa
GenBank accession 
number		 BC044577 Gene ID (NCBI) 9645
Gene symbol MICAL2 Synonyms DKFZp686H03148, DKFZp686H2469, KIAA0750, MICAL2, MICAL2PV1, MICAL2PV2, Protein MICAL 2
Background MICAL2抗体

MICALs (Molecules Interacting with CasL) are atypical multidomain flavoenzymes with diverse cellular functions.There are three known isoforms, MICAL1, MICAL2 and MICAL3, as well as the MICAL-like proteins MICAL-L1 and MICAL-L2. MICAL2 has three conserved domains: an N-terminal flavin adenine dinucleotide (FAD) binding domain, a calponin homology (CH) domain and a Lin11, Isl-1 and Mec-3 (LIM) domain. It has been demonstrated that MICAL2 could regulate actin stress fibers and is required for normal actin organization. In addition, MICAL2-PV, a novel splicing variants of MICAL2, has been reported to be involved in cancer progression of prostate cancer. This antibody can recognize both MICAL2 and MICAL2-PV. This antibody recognizes various isoforms of MICAL2 around 90-95 kDa or 109-112 kDa. MICAL2抗体

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