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上海信裕生物科技有限公司
YY1AP1抗体

YY1AP1抗体

商家询价

产品名称： YY1AP1抗体

英文名称： Antibody

产品编号： XY 10425-1-

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 YY1AP1抗体Applications

In-house applications ELISA, IF, WB     Application not tested? Please see our Guarantee.
Species specificity Human; other species not tested.
Images
Prev1NextView more validation data
  • 10425-1-AP;MDA-MB-231 cellsMDA-MB-231 cells were subjected to SDS PAGE followed by western blot with 10425-1-AP(YY1AP1 antibody) at dilution of 1:800
  • 10425-1-AP;HepG2Immunofluorescent analysis of HepG2 cells, using YY1AP1 antibody 10425-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
Positive WB detected in MDA-MB-231 cells
Positive IF detected in HepG2 cells
Recommended dilution WB : 1:200-1:2000
IF : 1:10-1:100
 YY1AP1抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information YY1AP1抗体
Immunogen YY1AP1 fusion protein ag0692 Full name YY1 associated protein 1
Calculated molecular
weight		 75 kDa Observed molecular 
weight		 75 kDa and 50 kDa
GenBank accession 
number		 BC003500 Gene ID (NCBI) 55249
Gene symbol YY1AP1 Synonyms FLJ10875, FLJ13914, HCCA1, HCCA2, YAP, YY1 associated protein 1, YY1AP, YY1AP1
Background

YY1AP1 (YY1 associated protein 1), also known as HCCA2 (hepatocellular carcinoma-associated protein 2) or YY1AP, is a 796 amino acid protein that localizes to both the nucleus and the cytoplasm and exists as seven alternatively spliced isoforms. We detected 75 kDa and 50 kDa two isoforms. YY1AP1 is expressed ubiquitously with notable expression in lung, brain, spleen, pancreas, small intestine, heart, colon and skeletal muscle, YY1AP1 interacts with and enhances the transcriptional activation activity of YY1. YY1AP1 is expressed at high levels in liver carcinomas, suggesting a role in tumor transformation and metastasis. YY1AP1 may play a role in cell cycle regulation. YY1AP1抗体

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