Murine & Rat Growth Factors & Cytokines
Recombinant Rat VEGF165





 





		Synonyms :
Vascular Endothelial Growth Factor, VPF, Folliculostellate cell-derived growth factor, Glioma-derived endothelial cell mitogen



		Description :
VEGF is a potent growth and angiogenic cytokine.  It stimulates proliferation and survival of endothellial cells, and promotes angiogenesis and vascular permeability.  Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis.  Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes.  VEGF signals through the three receptors; fms-like tyrosine kinase(flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product.  Recombinant rat VEGF is a 38.5 kDa disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.



		Catalog #:
400-31



		Source :
E.coli



		Purity :
Greater than 98% by SDS-PAGE gel and HPLC analyses.



		Endotoxin Level :
Endotoxin level is less than 0.1 ng per μg (1EU/μg).



		Biological Activity :
Determined by the dose-dependent stimulation of the proliferation of Human umbilical vein endothelial cells (HUVEC).  The expected ED50 is 4.0-8.0 ng/ml.



                AA Sequence :
MAPTTEGEQK AHEVVKFMDV YQRSYCRPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCAGC CNDEALECVP TSESNVTMQI MRIKPHQSQH IGEMSFLQHS RCECRPKKDR TKPEKHCEPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR 



		PubMed Link :
VEGF+AND+rat


Country of Origin :
USA
















        Size A
2μg
$80 
 


 



        Size B
10μg
$195 
 


 



        Size C
1mg
$3900 
 


 















Special 
                    Sizes: 
 Many products can be ordered in custom sizes. Please click here to contact Peprotech with your request.





Usage:
For Research Use Only.  Not for use in diagnostic or therapeutic procedures.