XRCC4抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
XRCC4抗体

XRCC4抗体

商家询价

产品名称： XRCC4抗体

英文名称： XRCC4Antibody

产品编号： XY15817-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 XRCC4抗体Applications

Tested Applications: ELISA, WB, IHC, IP
Cited applications WB
Specificity Reaction: Human, Rat; Other species are not tested.Please decide the specificity by homology
Cited species Human
Positive WB detected in K-562 cells, COLO 320 cells, HepG2 cells
Positive IP detected in HepG2 cells
Positive IHC detected in Human breast cancer tissue, rat small intestine tissue, rat testis tissue
Recommended dilution WB : 1:1000-1:10000
IP : 1:200-1:2000
IHC : 1:20-1:200
 XRCC4抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Images
Prev12NextView more validation data
  • 15817-1-AP;K-562 cellsK-562 cells were subjected to SDS PAGE followed by western blot with 15817-1-AP(XRCC4 antibody) at dilution of 1:1000
  • 15817-1-AP;human breast cancerImmunohistochemical of paraffin-embedded human breast cancer using 15817-1-AP(XRCC4 antibody) at dilution of 1:100 (under 10x lens)
  • 15817-1-AP;human breast cancerImmunohistochemical of paraffin-embedded human breast cancer using 15817-1-AP(XRCC4 antibody) at dilution of 1:100 (under 40x lens)
  • 15817-1-AP;HepG2 cellsIP Result of anti-XRCC4 (IP:15817-1-AP, 4ug; Detection:15817-1-AP 1:800) with HepG2 cells lysate 3200ug.
Product Information XRCC4抗体
Source: Rabbit Purify: Antigen affinity purification
IsoType: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.
Immunogen Information
Immunogen: XRCC4 fusion protein ag8606 Full Name: X-ray repair complementing defective repair in Chinese hamster cells 4
Caculated Molecular
Weight:		 310aa,35 kDa Observed Molecular 
Weight:		 55kd
GenbankNo BC005259 GeneID: 7518
Symbol XRCC4 Synonyms DNA repair protein XRCC4, XRCC4
Background

There are at least two pathways for eukaryotes to repair DNA double-strand breaks: homologous recombination and nonhomologous end joining(NHEJ). XRCC4 is one of the core machiney of NHEJ that requied for double-strand break repair and V(D)J recombination. The DNA ligase IV(LIG4)-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. XRCC4抗体

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