Human Growth Factors & Cytokines
Recombinant Human WISP-1





 





		Synonyms :
WNT-1 inducible signaling pathway protein-1, CCN4, Wnt-1-induced secreted protein



		Description :
WISP-1 is a member of the CCN family of secreted cysteine rich regulatory proteins.  It is expressed in the heart, kidney, lung, pancreas, placenta, ovary, small intestine and spleen.  WISP-1 is a beta catenin regulated protein that can contribute to tumorigenesis and has also been shown to play a role in bone development and fracture repair. Human WISP-1 is a 38.1 kDa protein containing 346 amino acid residues. It is composed of four distinct structural domains (modules); the IGF binding protein (IGFBP) domain, the von Willebrand Factor C (VWFC) domain, the thrombospondin type-1 repeat (TSP type-1) domain, and a C-terminal cystine knot-like (CTCK) domain.



		Catalog #:
120-18



		Source :
E.coli



		Purity :
Greater than 98% by SDS-PAGE gel and HPLC analyses



		Endotoxin Level :
Endotoxin level is less than 0.1 ng per μg (1EU/μg).



		Biological Activity :
The ED50 was determined by the dose-dependant proliferation of the MCF-7 cell line.  The expected ED50 for this effect is 1.0-3.0 μg/ml.






Selected References :
Selected List of References Citing This PeproTech Product



                AA Sequence :
TALSPAPTTM DFTPAPLEDT SSRPQFCKWP CECPPSPPRC PLGVSLITDG CECCKMCAQQ LGDNCTEAAI CDPHRGLYCD YSGDRPRYAI GVCAQVVGVG CVLDGVRYNN GQSFQPNCKY NCTCIDGAVG CTPLCLRVRP PRLWCPHPRR VSIPGHCCEQ WVCEDDAKRP RKTAPRDTGA FDAVGEVEAW HRNCIAYTSP WSPCSTSCGL GVSTRISNVN AQCWPEQESR LCNLRPCDVD IHTLIKAGKK CLAVYQPEAS MNFTLAGCIS TRSYQPKYCG VCMDNRCCIP YKSKTIDVSF QCPDGLGFSR QVLWINACFC NLSCRNPNDI FADLESYPDF SEIAN 



		PubMed Link :
WISP-1+OR+CCN4


Country of Origin :
USA
















        Size A
5μg
$80 
 


 



        Size B
20μg
$195 
 


 



        Size C
1mg
$3600 
 


 















Special 
                    Sizes: 
 Many products can be ordered in custom sizes. Please click here to contact Peprotech with your request.





Usage:
For Research Use Only.  Not for use in diagnostic or therapeutic procedures.