SKIV2L 抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
SKIV2L 抗体

SKIV2L 抗体

商家询价

产品名称: SKIV2L 抗体

英文名称: SKIV2L Antibody

产品编号: XY11462-1

产品价格: null

产品产地: 中国/美国

品牌商标: XYbscience

更新时间: 2023-08-17T09:55:27

使用范围: WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
  • 联系人 : 徐经理
  • 地址 : 上海市闵行莘庄工业区春东路508号A1-2F
  • 邮编 : 200612
  • 所在区域 : 上海
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 SKIV2L 抗体Applications

In-house applications ELISA, WB, IP     Application not tested? Please see our Guarantee.
Published applications IHC, WB Publications 3 citations –view here
Species specificity Human,Mouse,Rat; other species not tested.
Published Species Human, mouse
Images
Prev1NextView more validation data
  • 11462-1-AP;HEK-293 cellsHEK-293 cells were subjected to SDS PAGE followed by western blot with 11462-1-AP( SKIV2L Antibody) at dilution of 1:600
  • 11462-1-AP;HepG2 cellsIP Result of anti-SKIV2L (IP:11462-1-AP, 4ug; Detection:11462-1-AP 1:600) with HepG2 cells lysate 3200ug.
Positive WB detected in HEK-293 cells, COLO 320 cells, HepG2 cells, human kidney tissue, Jurkat cells
Positive IP detected in HepG2 cells
Recommended dilution WB : 1:200-1:2000
IP : 1:200-1:2000
 SKIV2L 抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
 SKIV2L 抗体
Immunogen SKIV2L fusion protein ag1977 Full name Superkiller viralicidic activity 2-like (S. cerevisiae)
Calculated molecular
weight
1246aa,138 kDa Observed molecular 
weight
138kd
GenBank accession 
number
BC015758 Gene ID (NCBI) 6499
Gene symbol SKIV2L Synonyms 170A, DDX13, Helicase like protein, Helicase SKI2W, HLP, SKI2, SKI2W, SKIV2, SKIV2L, W
Background

The Ski complex is a multiprotein complex required for exosome-mediated RNA surveillance, including the regulation of normal mRNA and the decay of nonfunctional mRNA. Component of the SKI complex which is thought to be involved in exosome-mediated RNA decay and associates with transcriptionally active genes in a manner dependent on PAF1 complex (PAF1C) [PMID:22444670]. SKIV2L , one component of the Ski complex, acts as an RNA helicase with a role in exosome recruitment or activation. It is involved in the degradation of RNAs by the exosome and may have a role in autophagy [PMID:11719186]. SKIV2L 抗体

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