JUN (phospho S63) polyclonal antibody
产品名称： JUN (phospho S63) polyclonal antibody
英文名称： JUN (phospho S63) polyclonal antibody
产品编号： PAB12616
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of JUN.
- Immunogen:
- Synthetic phosphopeptide corresponding to residues surrounding S63 of human JUN.
- Sequence:
- LTSPD
- Host:
- Rabbit
- Theoretical MW (kDa):
- 48
- Reactivity:
- Bovine, Dog, Human, Mouse, Rat
- Specificity:
- This antibody recognizes ~48 KDa of human JUN protein. It does not recognize non-phosphorylated peptides.
- Form:
- Liquid
- Storage Buffer:
- In PBS, pH 7.2 (10% Proclin300)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Western Blot (0.1-1 ug/mL)
ELISA (0.01-0.1 ug/mL)
Immunoprecipitation (2-5 ug/mL)
The optimal working dilution should be determined by the end user.
- Publication Reference
- 1.
- Indirubin-3'-oxime inhibits c-Jun NH2-terminal kinase: anti-apoptotic effect in cerebellar granule neurons.
Xie Y, Liu Y, Ma C, Yuan Z, Wang W, Zhu Z, Gao G, Liu X, Yuan H, Chen R, Huang S, Wang X, Zhu X, Wang X, Mao Z, Li M.Neurosci Lett. 2004 Sep 9;367(3):355-9.
- Applications
- Western Blot (Cell lysate)
- The cell lysate derived from UV treated NIH/3T3 cells was immunoprobed by JUN (phospho S63) polyclonal antibody (Cat # PAB12616) at 1 : 500. An immunoreactive band is observed around ~ 48kDa (lane 1). This band is blocked by pre-incubation with immunizing peptide (Lane 2).
- Entrez GeneID:
- 3725
- Gene Name:
- JUN
- Gene Alias:
- AP-1,AP1,c-Jun
- Gene Description:
- jun oncogene
- Omim ID:
- 165160
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. [provided by RefSeq
- Other Designations:
- Jun activation domain binding protein,OTTHUMP00000010036,activator protein 1,enhancer-binding protein AP1,v-jun avian sarcoma virus 17 oncogene homolog,v-jun sarcoma virus 17 oncogene homolog
- Gene Pathway
- B cell receptor signaling pathway
- Colorectal cancer
- Epithelial cell signaling in Helicobacter pylori infection
- ErbB signaling pathway
- Focal adhesion
- GnRH signaling pathway
- MAPK signaling pathway
- Neurotrophin signaling pathway
- Pathways in cancer
- Renal cell carcinoma
- T cell receptor signaling pathway
- Toll-like receptor signaling pathway
- Wnt signaling pathway
- Related Disease
- Arthritis, Reactive
- Asthma
- Asthma
- Breast cancer
- Breast Neoplasms
- Bronchiolitis, Viral
- Campylobacter Infections
- Cardiovascular Diseases
- Chronic Disease
- Crohn Disease
- Crohn's disease
- Diabetes Mellitus, Type 2
- Disease Models, Animal
- Edema
- Genetic Predisposition to Disease
- Infant, Premature, Diseases
- Kidney Failure, Chronic
- Ovarian Neoplasms
- Respiratory Syncytial Virus Infections