PKN1 (Human) Recombinant Protein
产品名称： PKN1 (Human) Recombinant Protein
英文名称： PKN1 (Human) Recombinant Protein
产品编号： P4768
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human PKN1 (NM_002741, 1 a.a. - 942 a.a.) full-length recombinant protein with GST-His tag expressed in Sf9 cells.
- Theoretical MW (kDa):
- 136.910
- Form:
- Liquid
- Preparation Method:
- Insect cell (Sf9) expression system
- Purification:
- One-step affinity purification using GSH agarose
- Concentration:
- 0.164 ug/uL
- Activity:
- 2 pmol/ug x min
- Storage Buffer:
- In 50 mM Hepes-NaOH, 100 mM NaCl, pH 7.5. (5 mM DTT, 4 mM reduced glutathione, 20% glycerol)
- Storage Instruction:
- Store at -80°C.
Aliquot to avoid repeated freezing and thawing
- Quality Control Testing:
- 2 ug/lane SDS-PAGE Stained with Coomassie Blue
- Note:
- Result of activity analysis
-
- Application Image
- Functional Study
- SDS-PAGE
- Entrez GeneID:
- 5585
- Protein Accession#:
- NM_002741
- Gene Name:
- PKN1
- Gene Alias:
- DBK,MGC46204,PAK1,PKN,PKN-ALPHA,PRK1,PRKCL1
- Gene Description:
- protein kinase N1
- Omim ID:
- 601032
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq
- Other Designations:
- protein kinase C-like 1,protein kinase C-like PKN,protein kinase C-related kinase 1,serine-threonine kinase N,serine/threonine protein kinase N
- Related Disease