Anti-XPC Polyclonal Antibody
产品名称: Anti-XPC Polyclonal Antibody
英文名称: XP3;RAD4;XPCC;p125
产品编号: K007896P
产品价格: null
产品产地: 北京
品牌商标: Solarbio
更新时间: null
使用范围: IHC
北京索莱宝科技有限公司--实验室产品
- 联系人 :
- 地址 : 北京市通州区马驹桥联东U谷景盛南四街85A三层
- 邮编 :
- 所在区域 : 北京
- 电话 : 010-563*1250 点击查看
- 传真 : 点击查看
- 邮箱 : 2748554845@qq.com
The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide excision repair (NER). The encoded protein is important for damage sensing and DNA binding, and shows a preference for single-stranded DNA. Mutations in this gene or some other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.