SOD3 monoclonal antibody, clone 1H12
产品名称： SOD3 monoclonal antibody, clone 1H12
英文名称： SOD3 monoclonal antibody, clone 1H12
产品编号： MAB0749
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant SOD3.
- Immunogen:
- Recombinant protein corresponding to amino acids 19-240 of human SOD3.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Ammonium sulfate precipitation
- Concentration:
- 1 mg/mL
- Isotype:
- IgG2b, kappa
- Storage Buffer:
- In HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:1800)
Immunoprecipitation (1 ul)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- The structure of holo and metal-deficient wild-type human Cu, Zn superoxide dismutase and its relevance to familial amyotrophic lateral sclerosis.
Strange RW, Antonyuk S, Hough MA, Doucette PA, Rodriguez JA, Hart PJ, Hayward LJ, Valentine JS, Hasnain SS.J Mol Biol. 2003 May 9;328(4):877-91.
- 2.
- Suppression of manganese superoxide dismutase augments sensitivity to radiation, hyperthermia and doxorubicin in colon cancer cell lines by inducing apoptosis.
Kuninaka S, Ichinose Y, Koja K, Toh Y.Br J Cancer. 2000 Oct;83(7):928-34.
- Application Image
- Western Blot (Transfected lysate)
- enlarge
- Immunohistochemistry
- Immunoprecipitation
- ELISA
- Entrez GeneID:
- 6649
- Gene Name:
- SOD3
- Gene Alias:
- EC-SOD,MGC20077
- Gene Description:
- superoxide dismutase 3, extracellular
- Omim ID:
- 185490
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide radicals into hydrogen peroxide and oxygen. The product of this gene is thought to protect the brain, lungs, and other tissues from oxidative stress. The protein is secreted into the extracellular space and forms a glycosylated homotetramer that is anchored to the extracellular matrix (ECM) and cell surfaces through an interaction with heparan sulfate proteoglycan and collagen. A fraction of the protein is cleaved near the C-terminus before secretion to generate circulating tetramers that do not interact with the ECM. [provided by RefSeq
- Other Designations:
- OTTHUMP00000158715
- Related Disease
- Acute Lung Injury
- Alzheimer Disease
- Alzheimer disease
- Arthritis, Rheumatoid
- Asbestosis
- Atherosclerosis
- Atherosclerosis
- Behcet Syndrome
- Birth Weight
- Brain Neoplasms
- Bronchial Hyperreactivity
- Calcinosis
- Cardiovascular Diseases
- Cerebral Infarction
- Chorioamnionitis
- Cognition
- Coronary Artery Disease
- Diabetes Mellitus
- Diabetes Mellitus, Type 1