FITC标记的ZNHIT2蛋白抗体
产品名称： FITC标记的ZNHIT2蛋白抗体
英文名称： Anti-ZNHIT2/FITC
产品编号： HZ-16415R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-ZNHIT2/FITC Conjugated antibody
FITC标记的ZNHIT2蛋白抗体
| 英文名称 | Anti-ZNHIT2/FITC |
| 中文名称 | FITC标记的ZNHIT2蛋白抗体 |
| 别 名 | C11orf5; FON; MGC120285; MGC120286; OTTHUMP00000230419; Protein FON; Zinc finger HIT domain-containing protein 2; Zinc finger HIT type containing 2; zinc finger, HIT domain containing 2; zinc finger, HIT type 2; ZNHI2_HUMAN; ZNHIT2. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 转录调节因子 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 45kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ZNHIT2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: ZNHIT2 (zinc finger, HIT-type containing 2), also known as FON, is a 403 amino acid protein that is highly expressed in the seminiferous tubules of testis, with low expression in other tissues. Containing one HIT-type zinc finger, ZNHIT2 is encoded by a gene that maps to human chromosome 11, which comprises approximately 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes. Tissue Specificity: Low expression in most tissues; highly expressed in testis. Similarity: Contains 1 HIT-type zinc finger. Database links: Entrez Gene: 741 Human Entrez Gene: 539138 Cow Entrez Gene: 100514699 Pig Entrez Gene: 309177 Rat Omim: 604575 Human SwissProt: Q2TBW5 Cow SwissProt: Q9UHR6 Human Unigene: 41757 Cow Unigene: 121025 Human Unigene: 19362 Pig Unigene: 18470 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application |
znhit2（锌手指，打型氟2），也知道知道的一样，是一个403氨基酸系高蛋白，这是在睾丸生精小管，与低表达，在其他tissues。。。。。。。含一个HIT型锌指的是，znhit2编码的基因，映射到人类染色体11，这comprises大约4%的人基因组DNA是考虑A基因和染色体病协会的重。11对染色体编码的ATM基因是重要的调节细胞周期和凋亡期阻滞后的双链DNA breaks。。。。。。。ATM突变的引线的紊乱的知名ataxia为共济失调性毛细血管扩张症。在血液性疾病的sickle细胞贫血和地中海贫血是由HBB基因突变引起的，在肾母细胞瘤肿瘤，wagr和丹尼斯Drash综合征-综合征伴是突变的WT1基因。耶韦尔和朗格-尼尔森的综合征，征杰克布森，尼曼-匹克病，遗传angioedema和史密斯- lemli Opitz综合征是也associate